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Direct loading of iTEP-delivered CTL epitope onto MHC Class I complexes on the dendritic cell surface

Cytotoxic T lymphocyte (CTL)-mediated immune responses are the primary defense mechanism against cancer and infection. CTL epitope peptides have been used as vaccines to boost CTL responses; however, the efficacy of these peptides is suboptimal. Under current vaccine formulation and delivery strateg...

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Detalhes bibliográficos
Publicado no:Mol Pharm
Main Authors: Dong, Shuyun, Wang, Peng, Zhao, Peng, Chen, Mingnan
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630454/
https://ncbi.nlm.nih.gov/pubmed/28789525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.7b00367
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