GATA2 regulates the erythropoietin receptor in t(12;21) ALL

The t(12;21) (p13;q22) chromosomal translocation resulting in the ETV6/RUNX1 fusion gene is the most frequent structural cytogenetic abnormality in children with acute lymphoblastic leukemia (ALL). The erythropoietin receptor (EPOR), usually associated with erythroid progenitor cells, is highly expr...

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Detalles Bibliográficos
Publicado en:Oncotarget
Autores principales: Gaine, Marie E., Sharpe, Daniel J., Smith, James S., Colyer, Hilary A.A., Hodges, Vivien M., Lappin, Terry R., Mills, Ken I.
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630392/
https://ncbi.nlm.nih.gov/pubmed/29029492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19792
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