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Display of DNA on Nanoparticles for Targeting Antigen Presenting Cells
Efficient delivery of antigens is of paramount concern in immunotherapies. We aimed to target antigen presenting cells (APCs) by conjugating CpG oligonucleotides to an E2 protein nanoparticle surface (CpG-PEG-E2). Compared to E2 alone, we observed ~4-fold increase of in vitro APC uptake of both CpG-...
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| Yayımlandı: | ACS Biomater Sci Eng |
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| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2017
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5630166/ https://ncbi.nlm.nih.gov/pubmed/28989957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsbiomaterials.7b00148 |
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