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Neuronal inhibition of the autophagy nucleation complex extends life span in post-reproductive C. elegans

Autophagy is a ubiquitous catabolic process that causes cellular bulk degradation of cytoplasmic components and is generally associated with positive effects on health and longevity. Inactivation of autophagy has been linked with detrimental effects on cells and organisms. The antagonistic pleiotrop...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Genes Dev
Egile Nagusiak: Wilhelm, Thomas, Byrne, Jonathan, Medina, Rebeca, Kolundžić, Ena, Geisinger, Johannes, Hajduskova, Martina, Tursun, Baris, Richly, Holger
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630021/
https://ncbi.nlm.nih.gov/pubmed/28882853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.301648.117
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