Microarray analysis of bone marrow lesions in osteoarthritis demonstrates upregulation of genes implicated in osteochondral turnover, neurogenesis and inflammation

OBJECTIVE: Bone marrow lesions (BMLs) are well described in osteoarthritis (OA) using MRI and are associated with pain, but little is known about their pathological characteristics and gene expression. We evaluated BMLs using novel tissue analysis tools to gain a deeper understanding of their cellul...

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Опубликовано в: :Ann Rheum Dis
Главные авторы: Kuttapitiya, Anasuya, Assi, Lena, Laing, Ken, Hing, Caroline, Mitchell, Philip, Whitley, Guy, Harrison, Abiola, Howe, Franklyn A, Ejindu, Vivian, Heron, Christine, Sofat, Nidhi
Формат: Artigo
Язык:Inglês
Опубликовано: BMJ Publishing Group 2017
Предметы:
Basic and Translational Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629942/
https://ncbi.nlm.nih.gov/pubmed/28705915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2017-211396
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