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Association between habenula dysfunction and motivational symptoms in unmedicated major depressive disorder

The lateral habenula plays a central role in reward and punishment processing and has been suggested to drive the cardinal symptom of anhedonia in depression. This hypothesis is largely based on observations of habenula hypermetabolism in animal models of depression, but the activity of habenula and...

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Detalhes bibliográficos
Publicado no:Soc Cogn Affect Neurosci
Main Authors: Liu, Wen-Hua, Valton, Vincent, Wang, Ling-Zhi, Zhu, Yu-Hua, Roiser, Jonathan P.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629818/
https://ncbi.nlm.nih.gov/pubmed/28575424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/scan/nsx074
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