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Roles of alternative splicing in modulating transcriptional regulation

BACKGROUND: The ability of a transcription factor to regulate its targets is modulated by a variety of genetic and epigenetic mechanisms. Alternative splicing can modulate gene function by adding or removing certain protein domains, and therefore affect the activity of protein. Reverse engineering o...

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Detalhes bibliográficos
Publicado no:BMC Syst Biol
Main Authors: Li, Jin, Wang, Yang, Rao, Xi, Wang, Yue, Feng, Weixing, Liang, Hong, Liu, Yunlong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629561/
https://ncbi.nlm.nih.gov/pubmed/28984199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-017-0465-6
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