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Roles of alternative splicing in modulating transcriptional regulation
BACKGROUND: The ability of a transcription factor to regulate its targets is modulated by a variety of genetic and epigenetic mechanisms. Alternative splicing can modulate gene function by adding or removing certain protein domains, and therefore affect the activity of protein. Reverse engineering o...
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Publicado no: | BMC Syst Biol |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5629561/ https://ncbi.nlm.nih.gov/pubmed/28984199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-017-0465-6 |
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