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System modeling reveals the molecular mechanisms of HSC cell cycle alteration mediated by Maff and Egr3 under leukemia

BACKGROUND: Molecular mechanisms of the functional alteration of hematopoietic stem cells (HSCs) in leukemic environment attract intensive research interests. As known in previous researches, Maff and Egr3 are two important genes having opposite functions on cell cycle; however, they are both highly...

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Detalhes bibliográficos
Publicado no:BMC Syst Biol
Main Authors: Li, Rudong, Wang, Yin, Cheng, Hui, Liu, Gang, Cheng, Tao, Liu, Yunlong, Liu, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629552/
https://ncbi.nlm.nih.gov/pubmed/28984203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-017-0467-4
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