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Polyfunctional response by ImmTAC (IMCgp100) redirected CD8(+) and CD4(+) T cells

The success of immune system‐based cancer therapies depends on a broad immune response engaging a range of effector cells and mechanisms. Immune mobilizing monoclonal T cell receptors (TCRs) against cancer (ImmTAC™ molecules: fusion proteins consisting of a soluble, affinity enhanced TCR and an anti...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Boudousquie, Caroline, Bossi, Giovanna, Hurst, Jacob M., Rygiel, Karolina A., Jakobsen, Bent K., Hassan, Namir J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629433/
https://ncbi.nlm.nih.gov/pubmed/28640942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12779
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