MIP-MAP: High-Throughput Mapping of Caenorhabditis elegans Temperature-Sensitive Mutants via Molecular Inversion Probes

Mutants remain a powerful means for dissecting gene function in model organisms such as Caenorhabditis elegans. Massively parallel sequencing has simplified the detection of variants after mutagenesis but determining precisely which change is responsible for phenotypic perturbation remains a key ste...

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Pubblicato in:Genetics
Autori principali: Mok, Calvin A., Au, Vinci, Thompson, Owen A., Edgley, Mark L., Gevirtzman, Louis, Yochem, John, Lowry, Joshua, Memar, Nadin, Wallenfang, Matthew R., Rasoloson, Dominique, Bowerman, Bruce, Schnabel, Ralf, Seydoux, Geraldine, Moerman, Donald G., Waterston, Robert H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Genetics Society of America 2017
Soggetti:
Investigations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629315/
https://ncbi.nlm.nih.gov/pubmed/28827289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.117.300179
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