Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth

Lung cancer is the leading cause of cancer mortality worldwide, with squamous cell carcinoma (SQCC) being the second most common form. SQCCs are thought to originate in bronchial basal cells through an injury response to smoking, which results in this stem cell population committing to hyperplastic...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Proteomics
Autori principali: Kim, Bo Ram, Coyaud, Etienne, Laurent, Estelle M. N., St-Germain, Jonathan, Van de Laar, Emily, Tsao, Ming-Sound, Raught, Brian, Moghal, Nadeem
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2017
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629269/
https://ncbi.nlm.nih.gov/pubmed/28794006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M116.064451
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