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Identification of Fc Gamma Receptor Glycoforms That Produce Differential Binding Kinetics for Rituximab
Fc gamma receptors (FcγR) bind the Fc region of antibodies and therefore play a prominent role in antibody-dependent cell-based immune responses such as ADCC, CDC and ADCP. The immune effector cell activity is directly linked to a productive molecular engagement of FcγRs where both the protein and g...
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| Publicado no: | Mol Cell Proteomics |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Biochemistry and Molecular Biology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5629263/ https://ncbi.nlm.nih.gov/pubmed/28576848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M117.066944 |
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