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Identification of Fc Gamma Receptor Glycoforms That Produce Differential Binding Kinetics for Rituximab

Fc gamma receptors (FcγR) bind the Fc region of antibodies and therefore play a prominent role in antibody-dependent cell-based immune responses such as ADCC, CDC and ADCP. The immune effector cell activity is directly linked to a productive molecular engagement of FcγRs where both the protein and g...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Hayes, Jerrard M., Frostell, Asa, Karlsson, Robert, Müller, Steffen, Martín, Silvia Míllan, Pauers, Martin, Reuss, Franziska, Cosgrave, Eoin F., Anneren, Cecilia, Davey, Gavin P., Rudd, Pauline M.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629263/
https://ncbi.nlm.nih.gov/pubmed/28576848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M117.066944
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