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A Dual Function for Prickle in Regulating Frizzled Stability during Feedback-Dependent Amplification of Planar Polarity

The core planar polarity pathway coordinates epithelial cell polarity during animal development, and loss of its activity gives rise to a range of defects, from aberrant morphogenetic cell movements to failure to correctly orient structures, such as hairs and cilia. The core pathway functions via a...

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Bibliographische Detailangaben
Veröffentlicht in:Curr Biol
Hauptverfasser: Warrington, Samantha J., Strutt, Helen, Fisher, Katherine H., Strutt, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cell Press 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5628951/
https://ncbi.nlm.nih.gov/pubmed/28918952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2017.08.016
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