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CRISPR-mediated HDAC2 disruption identifies two distinct classes of target genes in human cells
The transcriptional functions of the class I histone deacetylases (HDACs) HDAC1 and HDAC2 are mainly viewed as both repressive and redundant based on murine knockout studies, but they may have additional independent roles and their physiological functions in human cells are not as clearly defined. T...
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| Publicado no: | PLoS One |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5628847/ https://ncbi.nlm.nih.gov/pubmed/28982113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185627 |
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