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Dexmedetomidine reduces the neuronal apoptosis related to cardiopulmonary bypass by inhibiting activation of the JAK2–STAT3 pathway

Cardiopulmonary bypass (CPB) constitutes one of the primary methodologies pertaining to cardiac surgery. However, this form of surgery can cause damage to the body. Many studies have reported that dexmedetomidine confers cerebral protection. In this study, we aimed to investigate the effect and mech...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Chen, Yanhua, Zhang, Xu, Zhang, Bingdong, He, Guodong, Zhou, Lifang, Xie, Yubo
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5628699/
https://ncbi.nlm.nih.gov/pubmed/29033541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S140644
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