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Downregulation of A20 increases the cytotoxicity of IFN-γ in hepatocellular carcinoma cells

Hepatocellular carcinoma (HCC) is a highly fatal disease mandating development of novel, effective therapeutic strategy. Interferon-gamma (IFN-γ) is a pleiotropic cytokine with immunomodulatory, antiviral, and antitumor effects. Although IFN-γ is a promising antitumor agent, its application is limit...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Yin, Lei, Fang, Zheng, Shen, Ning-jia, Qiu, Ying-he, Li, Ai-jun, Zhang, Yong-jie
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5628674/
https://ncbi.nlm.nih.gov/pubmed/29033545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S135993
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