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Genetic risk models: Influence of model size on risk estimates and precision

Disease risk estimation plays an important role in disease prevention. Many studies have found that the ability to predict risk improves as the number of risk single-nucleotide polymorphisms (SNPs) in the risk model increases. However, the width of the confidence interval of the risk estimate is oft...

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Detalles Bibliográficos
Publicado en:Genet Epidemiol
Main Authors: Shan, Ying, Tromp, Gerard, Kuivaniemi, Helena, Smelser, Diane T., Verma, Shefali S., Ritchie, Marylyn D., Elmore, James R., Carey, David J., Conley, Yvette P., Gorin, Michael B., Weeks, Daniel E.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5628612/
https://ncbi.nlm.nih.gov/pubmed/28198095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22035
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