Transmembrane TNF-α Density, but not Soluble TNF-α Level, is Associated with Primary Response to Infliximab in Inflammatory Bowel Disease

OBJECTIVES: Anti-tumor necrosis factor (TNF)-α agents like Infliximab (IFX) are effective in the treatment of inflammatory bowel diseases (IBDs) and are widely used. However, a considerable number of patients do not respond or lose response to this therapy. Preliminary evidence suggests that transme...

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Detalhes bibliográficos
Publicado no:Clin Transl Gastroenterol
Main Authors: Amini Kadijani, Azade, Asadzadeh Aghdaei, Hamid, Sorrentino, Dario, Mirzaei, Alireza, Shahrokh, Shabnam, Balaii, Hedieh, Nguyen, Vu Q, Mays, Jessica L, Reza Zali, Mohammad
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Contributions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5628358/
https://ncbi.nlm.nih.gov/pubmed/28914262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ctg.2017.44
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