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Isomer-specific chromatographic profiling yields highly sensitive and specific potential N-glycan biomarkers for epithelial ovarian cancer

Aberrant glycosylation has been observed for decades in essentially all types of cancer, and is now well established as an indicator of carcinogenesis. Mining the glycome for biomarkers, however, requires analytical methods that can rapidly separate, identify, and quantify isomeric glycans. We have...

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Detalhes bibliográficos
Publicado no:J Chromatogr A
Main Authors: Hua, Serenus, Williams, Cynthia C., Dimapasoc, Lauren M., Ro, Grace S., Ozcan, Sureyya, Miyamoto, Suzanne, Lebrilla, Carlito B., An, Hyun Joo, Leiserowitz, Gary S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5628020/
https://ncbi.nlm.nih.gov/pubmed/23380366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chroma.2012.12.079
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