A Stat6/Pten axis links cold exposure with T cell tolerance in adipose tissue

Obesity and type-2 diabetes are associated with tissue-inflammation and metabolic defects in fat depots. Foxp3(+)regulatory T(Treg) cells mediate T-cell tolerance, thereby controlling tissue inflammation. However, the molecular underpinnings how environmental stimuli interlink T-cell tolerance with...

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Publicado no:Cell Metab
Main Authors: Kälin, Stefanie, Becker, Maike, Ott, Verena B., Serr, Isabelle, Hosp, Fabian, Mollah, Mohammad M. H., Keipert, Susanne, Lamp, Daniel, Rohner-Jeanrenaud, Francoise, Flynn, Victoria K., Scherm, Martin G., Nascimento, Lucas F. R., Gerlach, Katharina, Popp, Vanessa, Dietzen, Sarah, Bopp, Tobias, Krishnamurthy, Purna, Kaplan, Mark H., Serrano, Manuel, Woods, Stephen C., Tripal, Philipp, Palmisano, Ralf, Jastroch, Martin, Blüher, Matthias, Wolfrum, Christian, Weigmann, Benno, Ziegler, Anette-Gabriele, Mann, Matthias, Tschöp, Matthias H., Daniel, Carolin
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627977/
https://ncbi.nlm.nih.gov/pubmed/28877454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2017.08.008
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