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Clinical Challenges in Targeting Anaplastic Lymphoma Kinase in Advanced Non-small Cell Lung Cancer

The revolution in individualized therapy for patients with advanced NSCLC has seen the emergence of a number of molecularly targeted therapies for distinct patient molecular subgroups. Activating anaplastic lymphoma kinase (ALK)-gene rearrangement has been detected in 3%–7% of NSCLC cases, and the A...

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Detalhes bibliográficos
Publicado no:Cancer Chemother Pharmacol
Main Authors: Vijayvergia, Namrata, Mehra, Ranee
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627646/
https://ncbi.nlm.nih.gov/pubmed/25135623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-014-2517-6
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