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The risk of type 2 oral polio vaccine use in post-cessation outbreak response

BACKGROUND: Wild type 2 poliovirus was last observed in 1999. The Sabin-strain oral polio vaccine type 2 (OPV2) was critical to eradication, but it is known to revert to a neurovirulent phenotype, causing vaccine-associated paralytic poliomyelitis. OPV2 is also transmissible and can establish circul...

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Detalhes bibliográficos
Publicado no:BMC Med
Main Authors: McCarthy, Kevin A., Chabot-Couture, Guillaume, Famulare, Michael, Lyons, Hil M., Mercer, Laina D.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627419/
https://ncbi.nlm.nih.gov/pubmed/28974220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-017-0937-y
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