Non-neutralizing Antibodies Targeting the V1V2 Domain of HIV Exhibit Strong Antibody-Dependent Cell-mediated Cytotoxic Activity

The development of an effective vaccine against HIV-1 has proven to be challenging. Broadly neutralizing antibodies (bNAbs), whilst exhibiting neutralization breadth and potency, are elicited only in a small subset of infected individuals and have yet to be induced by vaccination. Case-control studi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mayr, Luzia M., Decoville, Thomas, Schmidt, Sylvie, Laumond, Géraldine, Klingler, Jéromine, Ducloy, Camille, Bahram, Seiamak, Zolla-Pazner, Susan, Moog, Christiane
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627290/
https://ncbi.nlm.nih.gov/pubmed/28978939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12883-6
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