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Cyclotides Isolated from an Ipecac Root Extract Antagonize the Corticotropin Releasing Factor Type 1 Receptor

Cyclotides are plant derived, cystine-knot stabilized peptides characterized by their natural abundance, sequence variability and structural plasticity. They are abundantly expressed in Rubiaceae, Psychotrieae in particular. Previously the cyclotide kalata B7 was identified to modulate the human oxy...

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Bibliografische gegevens
Gepubliceerd in:Front Pharmacol
Hoofdauteurs: Fahradpour, Mohsen, Keov, Peter, Tognola, Carlotta, Perez-Santamarina, Estela, McCormick, Peter J., Ghassempour, Alireza, Gruber, Christian W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627009/
https://ncbi.nlm.nih.gov/pubmed/29033832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00616
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