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Transient MutS-Based Hypermutation System for Adaptive Evolution of Lactobacillus casei to Low pH
This study explored transient inactivation of the gene encoding the DNA mismatch repair enzyme MutS as a tool for adaptive evolution of Lactobacillus casei. MutS deletion derivatives of L. casei 12A and ATCC 334 were constructed and subjected to a 100-day adaptive evolution process to increase lacti...
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| Publicado no: | Appl Environ Microbiol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5627003/ https://ncbi.nlm.nih.gov/pubmed/28802267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01120-17 |
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