An Intramolecular Salt Bridge in Bacillus thuringiensis Cry4Ba Toxin Is Involved in the Stability of Helix α-3, Which Is Needed for Oligomerization and Insecticidal Activity

Bacillus thuringiensis three-domain Cry toxins kill insects by forming pores in the apical membrane of larval midgut cells. Oligomerization of the toxin is an important step for pore formation. Domain I helix α-3 participates in toxin oligomerization. Here we identify an intramolecular salt bridge w...

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Detaylı Bibliyografya
Yayımlandı:Appl Environ Microbiol
Asıl Yazarlar: Pacheco, Sabino, Gómez, Isabel, Sánchez, Jorge, García-Gómez, Blanca-Ines, Soberón, Mario, Bravo, Alejandra
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2017
Konular:
Invertebrate Microbiology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626994/
https://ncbi.nlm.nih.gov/pubmed/28802270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01515-17
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