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Entamoeba histolytica-Induced Mucin Exocytosis Is Mediated by VAMP8 and Is Critical in Mucosal Innate Host Defense

Intestinal mucus secretion is critical in maintaining mucosal host defense against a myriad of pathogens by preventing direct association with the epithelium. Entamoeba histolytica specifically binds colonic MUC2 mucin and also induces potent hypersecretion from goblet cells; however, characterizati...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Cornick, Steve, Moreau, France, Gaisano, Herbert Y., Chadee, Kris
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626970/
https://ncbi.nlm.nih.gov/pubmed/28974617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01323-17
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