One-Step Fabrication of Bone Morphogenetic Protein-2 Gene-Activated Porous Poly-L-Lactide Scaffold for Bone Induction

Bone morphogenetic protein 2 (BMP2) is an efficacious inducer for the osteogenesis of mesenchymal stem cells (MSCs). Conventional applications of BMP2 have involved either the direct incorporation of BMP2 protein or ex vivo BMP2 gene transfer into stem cells prior to their transplantation. These app...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Ther Methods Clin Dev
Hauptverfasser: Xue, Jingwen, Lin, Hang, Bean, Allison, Tang, Ying, Tan, Jian, Tuan, Rocky S., Wang, Bing
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Gene & Cell Therapy 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626914/
https://ncbi.nlm.nih.gov/pubmed/29018836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2017.08.008
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