Sphingosine-1-Phosphate Receptor 5 Modulates Early-Stage Processes during Fibrogenesis in a Mouse Model of Systemic Sclerosis: A Pilot Study

Systemic sclerosis (SSc) is a rare multi-organ autoimmune disease characterized by progressive skin fibrosis. Inflammation, type 2 immunity, and fibrogenic processes are involved in disease development and may be affected by sphingolipids. However, details about early-stage pathophysiological mechan...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Schmidt, Katrin G., Herrero San Juan, Martina, Trautmann, Sandra, Berninger, Lucija, Schwiebs, Anja, Ottenlinger, Florian M., Thomas, Dominique, Zaucke, Frank, Pfeilschifter, Josef M., Radeke, Heinfried H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626866/
https://ncbi.nlm.nih.gov/pubmed/29033951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01242
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