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Human intestinal organoids express histo-blood group antigens, bind norovirus VLPs, and support limited norovirus replication

Through pluripotent stem cell (PSC) technology, human intestinal organoids (HIOs) with remarkably similarity to the fetal intestine in cellular composition, architecture, and absorptive/secretory functions have been successfully developed, providing a useful in vitro model system to study the struct...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Zhang, Dongsheng, Tan, Ming, Zhong, Weiming, Xia, Ming, Huang, Pengwei, Jiang, Xi
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626734/
https://ncbi.nlm.nih.gov/pubmed/28974702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12736-2
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