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Human intestinal organoids express histo-blood group antigens, bind norovirus VLPs, and support limited norovirus replication

Through pluripotent stem cell (PSC) technology, human intestinal organoids (HIOs) with remarkably similarity to the fetal intestine in cellular composition, architecture, and absorptive/secretory functions have been successfully developed, providing a useful in vitro model system to study the struct...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Dongsheng, Tan, Ming, Zhong, Weiming, Xia, Ming, Huang, Pengwei, Jiang, Xi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626734/
https://ncbi.nlm.nih.gov/pubmed/28974702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12736-2
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