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Human intestinal organoids express histo-blood group antigens, bind norovirus VLPs, and support limited norovirus replication

Through pluripotent stem cell (PSC) technology, human intestinal organoids (HIOs) with remarkably similarity to the fetal intestine in cellular composition, architecture, and absorptive/secretory functions have been successfully developed, providing a useful in vitro model system to study the struct...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Zhang, Dongsheng, Tan, Ming, Zhong, Weiming, Xia, Ming, Huang, Pengwei, Jiang, Xi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626734/
https://ncbi.nlm.nih.gov/pubmed/28974702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12736-2
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