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Environmental perturbation of the circadian clock during pregnancy leads to transgenerational mood disorder-like behaviors in mice

It remains unknown whether chronic circadian disturbance (CCD) during pregnancy can lead to mood disorders in the offspring. Here we show that pregnant mice in the F0 generation that were exposed to CCD stress displayed depression-like behaviors, and produced offspring in the F1 and F2 generations t...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Zhang, Peng, Li, Guang, Li, Hui, Tan, XiaoQiu, Cheng, Hai-Ying Mary
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626699/
https://ncbi.nlm.nih.gov/pubmed/28974783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13067-y
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