Tobacco-specific carcinogens induce hypermethylation, DNA adducts and DNA damage in Bladder Cancer

Smoking is a major risk factor for the development of Bladder Cancer (BLCA); however, the functional consequences of the carcinogens in tobacco smoke and BLCA-associated metabolic alterations remains poorly defined. We assessed the metabolic profiles in BLCA smokers and non-smokers, and identified t...

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Detalhes bibliográficos
Publicado no:Cancer Prev Res (Phila)
Main Authors: Jin, Feng, Thaiparambil, Jose, Donepudi, Sri Ramya, Vantaku, Venkatrao, Piyarathna, Danthasinghe Waduge Badrajee, Maity, Suman, Krishnapuram, Rashmi, Putluri, Vasanta, Gu, Franklin, Purwaha, Preeti, Bhowmik, Salil Kumar, Ambati, Chandrashekar R, von Rundstedt, Friedrich-Carl, Roghmann, Florian, Berg, Sebastian, Noldus, Joachim, Rajapakshe, Kimal, Gödde, Daniel, Roth, Stephan, Störkel, Stephan, Degener, Stephan, Michailidis, George, Kaipparettu, Benny Abraham, Karanam, Balasubramanyam, Terris, Martha K., Kavuri, Shyam M, Lerner, Seth P., Kheradmand, Farrah, Coarfa, Cristian, Sreekumar, Arun, Lotan, Yair, El-Zein, Randa, Putluri, Nagireddy
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626664/
https://ncbi.nlm.nih.gov/pubmed/28851690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-17-0198
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