Chronic Ethanol Metabolism Inhibits Hepatic Mitochondrial Superoxide Dismutase via Lysine Acetylation

BACKGROUND: Chronic ethanol consumption is a major cause of liver disease worldwide. Oxidative stress is a known consequence of ethanol metabolism and is thought to contribute significantly to alcoholic liver disease (ALD). Therefore, elucidating pathways leading to sustained oxidative stress and do...

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Publicat a:Alcohol Clin Exp Res
Autors principals: Assiri, Mohammed A., Roy, Samantha R., Harris, Peter S., Ali, Hadi, Liang, Yongliang, Shearn, Colin T., Orlicky, David J., Roede, James R., Hirschey, Matthew D., Backos, Donald S., Fritz, Kristofer S.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626652/
https://ncbi.nlm.nih.gov/pubmed/28804911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.13473
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