S100A4 is a biomarker and regulator of glioma stem cells that is critical for mesenchymal transition in glioblastoma

Glioma stem cells (GSCs) and epithelial-mesenchymal transition (EMT) are strongly associated with therapy resistance and tumor recurrence, but the underlying mechanisms are incompletely understood. Here we show that S100A4 is a novel biomarker of GSCs. S100A4+ cells in gliomas are enriched with canc...

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Vydáno v:Cancer Res
Hlavní autoři: Chow, Kin-Hoe, Park, Hee Jung, George, Joshy, Yamamoto, Keiko, Gallup, Andrew D., Graber, Joel H., Chen, Yuanxin, Jiang, Wen, Steindler, Dennis A., Neilson, Eric G., Kim, Betty Y.S., Yun, Kyuson
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626628/
https://ncbi.nlm.nih.gov/pubmed/28807938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-1294
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