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Vascular endothelium plays a key role in directing pulmonary epithelial cell differentiation

The vascular endothelium is critical for induction of appropriate lineage differentiation in organogenesis. In this study, we report that dysfunctional pulmonary endothelium, resulting from the loss of matrix Gla protein (MGP), causes ectopic hepatic differentiation in the pulmonary epithelium. We d...

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Dettagli Bibliografici
Pubblicato in:J Cell Biol
Autori principali: Yao, Jiayi, Guihard, Pierre J., Wu, Xiuju, Blazquez-Medela, Ana M., Spencer, Melissa J., Jumabay, Medet, Tontonoz, Peter, Fogelman, Alan M., Boström, Kristina I., Yao, Yucheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626536/
https://ncbi.nlm.nih.gov/pubmed/28838957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201612122
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