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PPARγ in dendritic cells and T cells drives pathogenic type-2 effector responses in lung inflammation
Type-2 immune responses are well-established drivers of chronic inflammatory diseases, such as asthma, and represent a large burden on public health systems. The transcription factor PPARγ is known to promote M2-macrophage and alveolar macrophage development. Here, we report that PPARγ plays a key r...
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| Pubblicato in: | J Exp Med |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5626395/ https://ncbi.nlm.nih.gov/pubmed/28798029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20162069 |
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