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Predicting treatment outcomes of major depressive disorder by early improvement in painful physical symptoms: a pooled analysis of double-blind, placebo-controlled trials of duloxetine

OBJECTIVE: We determined if early improvement in painful physical symptoms (PPS) can be a predictor of remission in the treatment of major depressive disorder (MDD). METHODS: We included randomized, double-blind, parallel-group clinical trials of duloxetine (40–60 mg/day) versus placebo for the acut...

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Dades bibliogràfiques
Publicat a:Neuropsychiatr Dis Treat
Autors principals: Tokuoka, Hirofumi, Nishihara, Makoto, Fujikoshi, Shinji, Yoshikawa, Aki, Kuga, Atsushi
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626379/
https://ncbi.nlm.nih.gov/pubmed/29026309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/NDT.S143093
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