A mutagenesis-based approach identifies amino acids in the N-terminal part of Francisella tularensis IglE that critically control Type VI system-mediated secretion

The Gram-negative bacterium Francisella tularensis is the etiological agent of the zoonotic disease tularemia. Its life cycle is characterized by an ability to survive within phagocytic cells through phagosomal escape and replication in the cytosol, ultimately causing inflammasome activation and hos...

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Veröffentlicht in:Virulence
Hauptverfasser: Bröms, Jeanette E., Meyer, Lena, Sjöstedt, Anders
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2016
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Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626337/
https://ncbi.nlm.nih.gov/pubmed/27830989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21505594.2016.1258507
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