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Salt-inducible kinases (SIK) inhibition reduces RANKL-induced osteoclastogenesis

Osteoclasts are large multinucleated cells responsible for bone resorption. Excessive inflammatory activation of osteoclasts leads to bony erosions, which are the hallmark of several diseases such as rheumatoid arthritis (RA). Salt-inducible kinases (SIK) constitute a subfamily of kinases comprising...

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書目詳細資料
發表在:PLoS One
Main Authors: Lombardi, Maria Stella, Gilliéron, Corine, Berkelaar, Majoska, Gabay, Cem
格式: Artigo
語言:Inglês
出版: Public Library of Science 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626034/
https://ncbi.nlm.nih.gov/pubmed/28973003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185426
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