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Salt-inducible kinases (SIK) inhibition reduces RANKL-induced osteoclastogenesis
Osteoclasts are large multinucleated cells responsible for bone resorption. Excessive inflammatory activation of osteoclasts leads to bony erosions, which are the hallmark of several diseases such as rheumatoid arthritis (RA). Salt-inducible kinases (SIK) constitute a subfamily of kinases comprising...
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| Publicat a: | PLoS One |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5626034/ https://ncbi.nlm.nih.gov/pubmed/28973003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185426 |
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