Cryo-EM structure of the bacteriophage T4 isometric head at 3.3-Å resolution and its relevance to the assembly of icosahedral viruses

The 3.3-Å cryo-EM structure of the 860-Å-diameter isometric mutant bacteriophage T4 capsid has been determined. WT T4 has a prolate capsid characterized by triangulation numbers (T numbers) T(end) = 13 for end caps and T(mid) = 20 for midsection. A mutation in the major capsid protein, gp23, produce...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Chen, Zhenguo, Sun, Lei, Zhang, Zhihong, Fokine, Andrei, Padilla-Sanchez, Victor, Hanein, Dorit, Jiang, Wen, Rossmann, Michael G., Rao, Venigalla B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625921/
https://ncbi.nlm.nih.gov/pubmed/28893988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1708483114
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