Chiglitazar Preferentially Regulates Gene Expression via Configuration-Restricted Binding and Phosphorylation Inhibition of PPARγ

Type 2 diabetes mellitus is often treated with insulin-sensitizing drugs called thiazolidinediones (TZD), which improve insulin resistance and glycemic control. Despite their effectiveness in treating diabetes, these drugs provide little protection from eminent cardiovascular disease associated with...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PPAR Res
Päätekijät: Pan, De-Si, Wang, Wei, Liu, Nan-Song, Yang, Qian-Jiao, Zhang, Kun, Zhu, Jing-Zhong, Shan, Song, Li, Zhi-Bin, Ning, Zhi-Qiang, Huang, Laiqiang, Lu, Xian-Ping
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Hindawi 2017
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625810/
https://ncbi.nlm.nih.gov/pubmed/29056962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/4313561
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