Chiglitazar Preferentially Regulates Gene Expression via Configuration-Restricted Binding and Phosphorylation Inhibition of PPARγ

Type 2 diabetes mellitus is often treated with insulin-sensitizing drugs called thiazolidinediones (TZD), which improve insulin resistance and glycemic control. Despite their effectiveness in treating diabetes, these drugs provide little protection from eminent cardiovascular disease associated with...

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Enregistré dans:
Détails bibliographiques
Publié dans:PPAR Res
Auteurs principaux: Pan, De-Si, Wang, Wei, Liu, Nan-Song, Yang, Qian-Jiao, Zhang, Kun, Zhu, Jing-Zhong, Shan, Song, Li, Zhi-Bin, Ning, Zhi-Qiang, Huang, Laiqiang, Lu, Xian-Ping
Format: Artigo
Langue:Inglês
Publié: Hindawi 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625810/
https://ncbi.nlm.nih.gov/pubmed/29056962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/4313561
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