Suppression of SIRT2 and altered acetylation status of human pluripotent stem cells: possible link to metabolic switch during reprogramming

Primed human pluripotent stem cells (hPSCs) are highly dependent on glycolysis rather than oxidative phosphorylation, which is similar to the metabolic switch that occurs in cancer cells. However, the molecular mechanisms that underlie this metabolic reprogramming in hPSCs and its relevance to pluri...

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Bibliographic Details
Published in:BMB Rep
Main Authors: Kwon, Ok-Seon, Han, Min-Joon, Cha, Hyuk-Jin
Format: Artigo
Language:Inglês
Published: Korean Society for Biochemistry and Molecular Biology 2017
Subjects:
Perspective
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625689/
https://ncbi.nlm.nih.gov/pubmed/28683850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2017.50.9.119
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