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Modeling the architecture of the regulatory system controlling methylenomycin production in Streptomyces coelicolor

BACKGROUND: The antibiotic methylenomycin A is produced naturally by Streptomyces coelicolor A3(2), a model organism for streptomycetes. This compound is of particular interest to synthetic biologists because all of the associated biosynthetic, regulatory and resistance genes are located on a single...

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Библиографические подробности
Опубликовано в: :J Biol Eng
Главные авторы: Bowyer, Jack E., LC. de los Santos, Emmanuel, Styles, Kathryn M., Fullwood, Alex, Corre, Christophe, Bates, Declan G.
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625687/
https://ncbi.nlm.nih.gov/pubmed/29026441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13036-017-0071-6
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