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High-throughput RNAi screen for essential genes and drug synergistic combinations in colorectal cancer
Metastatic colorectal cancer is a leading cause of cancer death. However, current therapy options are limited to chemotherapy, with the addition of anti-EGFR antibodies for patients with RAS wild-type tumours. Novel drug targets, or drug combinations that induce a synergistic response, would be of g...
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Publicado no: | Sci Data |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5625556/ https://ncbi.nlm.nih.gov/pubmed/28972570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sdata.2017.139 |
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