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Externally controllable glycan presentation on nanoparticle surfaces to modulate lectin recognition

Nature dynamically controls carbohydrate expression on cells rather than static presentation. Here we report synthetic glycosylated nanoparticles that contain polymeric ‘gates’ to enable external control (via temperature changes) of glycan surface expression, as an alternative to enzymatic control i...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nanoscale Horiz
Prif Awduron: Won, Sangho, Richards, Sarah-Jane, Walker, Marc, Gibson, Matthew I.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Royal Society of Chemistry 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625543/
https://ncbi.nlm.nih.gov/pubmed/28989796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6nh00202a
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