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Highly Pathogenic New World Arenavirus Infection Activates the Pattern Recognition Receptor Protein Kinase R without Attenuating Virus Replication in Human Cells

The arenavirus family consists of several highly pathogenic viruses, including the Old World (OW) arenavirus Lassa fever virus (LASV) and the New World (NW) Junin virus (JUNV) and Machupo virus (MACV). Host response to infection by these pathogenic arenaviruses is distinct in many aspects. JUNV and...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Huang, Cheng, Kolokoltsova, Olga A., Mateer, Elizabeth J., Koma, Takaaki, Paessler, Slobodan
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625494/
https://ncbi.nlm.nih.gov/pubmed/28794024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01090-17
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