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Highly Pathogenic New World Arenavirus Infection Activates the Pattern Recognition Receptor Protein Kinase R without Attenuating Virus Replication in Human Cells

The arenavirus family consists of several highly pathogenic viruses, including the Old World (OW) arenavirus Lassa fever virus (LASV) and the New World (NW) Junin virus (JUNV) and Machupo virus (MACV). Host response to infection by these pathogenic arenaviruses is distinct in many aspects. JUNV and...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Huang, Cheng, Kolokoltsova, Olga A., Mateer, Elizabeth J., Koma, Takaaki, Paessler, Slobodan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625494/
https://ncbi.nlm.nih.gov/pubmed/28794024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01090-17
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