Adenylyl Cyclase 1 Is Required for Ethanol-Induced Locomotor Sensitization and Associated Increases in NMDA Receptor Phosphorylation and Function in the Dorsal Medial Striatum

Neuroadaptive responses to chronic ethanol, such as behavioral sensitization, are associated with N-methyl-D-aspartate receptor (NMDAR) recruitment. Ethanol enhances GluN2B-containing NMDAR function and phosphorylation (Tyr-1472) of the GluN2B-NMDAR subunit in the dorsal medial striatum (DMS) throug...

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Detalles Bibliográficos
Publicado en:J Pharmacol Exp Ther
Autores principales: Bosse, Kelly E., Oginsky, Max F., Susick, Laura L., Ramalingam, Sailesh, Ferrario, Carrie R., Conti, Alana C.
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2017
Materias:
Neuropharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625283/
https://ncbi.nlm.nih.gov/pubmed/28838956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.117.242321
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