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Asymmetric syntheses of 8-oxabicyclo[3,2,1]octane and 11-oxatricyclo[5.3.1.0]undecane from glycals

Herein, we describe an efficient method to prepare enantiomerically pure 8-oxabicyclo[3.2.1]octanes via gold(i)-catalyzed tandem 1,3-acyloxy migration/Ferrier rearrangement of glycal derived 1,6-enyne bearing propargylic carboxylates. The resultant compounds could then undergo interrupted Nazarov cy...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Liao, Hongze, Leng, Wei-Lin, Le Mai Hoang, Kim, Yao, Hui, He, Jingxi, Voo, Amanda Ying Hui, Liu, Xue-Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625258/
https://ncbi.nlm.nih.gov/pubmed/28989693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc02625k
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