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17β‐estradiol reduces Ca(v)1.2 channel abundance and attenuates Ca(2+)‐dependent contractions in coronary arteries
One mechanism by which the female sex may protect against elevated coronary vascular tone is inhibition of Ca(2+) entry into arterial smooth muscle cells (ASMCs). In vitro findings confirm that high estrogen concentrations directly inhibit voltage‐dependent Ca(v)1.2 channels in coronary ASMCs. For t...
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| Publicado en: | Pharmacol Res Perspect |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5625162/ https://ncbi.nlm.nih.gov/pubmed/28971605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.358 |
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