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17β‐estradiol reduces Ca(v)1.2 channel abundance and attenuates Ca(2+)‐dependent contractions in coronary arteries

One mechanism by which the female sex may protect against elevated coronary vascular tone is inhibition of Ca(2+) entry into arterial smooth muscle cells (ASMCs). In vitro findings confirm that high estrogen concentrations directly inhibit voltage‐dependent Ca(v)1.2 channels in coronary ASMCs. For t...

詳細記述

保存先:
書誌詳細
出版年:Pharmacol Res Perspect
主要な著者: Hill, Brent J.F., Dalton, Robin J., Joseph, Biny K., Thakali, Keshari M., Rusch, Nancy J.
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625162/
https://ncbi.nlm.nih.gov/pubmed/28971605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.358
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