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Versatile Roles of the Chromatin Remodeler CHD7 during Brain Development and Disease

CHD7 (Chromo-Helicase-DNA binding protein 7) protein is an ATP-dependent chromatin remodeler. Heterozygous mutation of the CHD7 gene causes a severe congenital disease known as CHARGE syndrome. Most CHARGE syndrome patients have brain structural anomalies, implicating an important role of CHD7 durin...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Feng, Weijun, Shao, Chunxuan, Liu, Hai-Kun
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625114/
https://ncbi.nlm.nih.gov/pubmed/29033785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00309
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